NFL week 10 schedule 2026: Games, times and predictions

NFL Week 10 runs from November 12 through November 16, with 14 games and the Bears, Broncos, Eagles and Buccaneers on bye. Quarterback health shapes several games, including Patrick Mahomes' elbow in Kansas City, J.J. McCarthy's hip for the Thursday night opener and Drew Lock starting again in Seattle.

Below is the full schedule, including kickoff times and game predictions, followed by a quick preview of every game.

This article is for informational purposes only and should not be construed as financial or investment advice. Past performance does not guarantee future results.

NFL Week 10 schedule, times and predictions

All kickoff times are Eastern Time (ET). The first team listed is the designated visiting team. New England Patriots vs Detroit Lions is a neutral-site game.

The percentages below show OG's market-implied win probabilities at the time of the update. Displayed percentages may not total 100%. Game predictions reflect our editorial assessment and may differ from the market. Neither guarantees an outcome.

Market data as of November 10, 2026. Schedule and team news last checked November 10, 2026. Prices and schedules may change.

Teams on bye: Chicago Bears, Denver Broncos, Philadelphia Eagles, Tampa Bay Buccaneers.

Washington Commanders vs New York Giants prediction

• Date: Thursday, November 12.
• Kickoff: 8:15 p.m. ET.
• OG win probabilities: Commanders 47%; Giants 55%.
• What to watch: J.J. McCarthy's hip and the Giants' protection.

J.J. McCarthy is questionable with a hip injury, and Giants coach John Harbaugh said he looks like he is going to play. The Giants have been sacked 27 times, tied for 27th, so a hobbled McCarthy faces a Washington defense that has built a plus-seven turnover margin. We give the Giants a slight edge if McCarthy takes the field. Washington's path to the upset runs through Jayden Daniels turning those takeaways into short fields.

New England Patriots vs Detroit Lions prediction

• Date: Sunday, November 15.
• Kickoff: 9:30 a.m. ET.
• OG win probabilities: Patriots 42%; Lions 60%.
• What to watch: Drake Maye's ball security against Detroit's pass rush.

Drake Maye threw three interceptions in the loss to Green Bay, and the Patriots sit tied for 31st in turnover margin. That meets a Lions pass rush third in the league in sacks and a run defense allowing 94 yards per game. We favor the Lions, who pair that pressure with Jared Goff and an offense scoring 27.8 points per game. New England needs clean pockets for Maye and no more short fields for Detroit.

Kansas City Chiefs vs Atlanta Falcons prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Chiefs 64%; Falcons 38%.
• What to watch: Patrick Mahomes' elbow after his Week 9 exit and return.

Patrick Mahomes is questionable with an elbow injury after leaving briefly against the Jets and returning to finish a 35-12 win. His protection holds up, with the Chiefs sacked only 11 times, tied for second fewest, against a Falcons defense with 20 sacks. Kansas City also allows just 17.9 points per game. Kansas City gets our pick. Atlanta has to win the ground battle with its 137 rushing yards per game and keep Michael Penix Jr. from handing back possessions.

Houston Texans vs Cleveland Browns prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Texans 69%; Browns 33%.
• What to watch: Houston's pass rush against Cleveland's protection.

C.J. Stroud threw for 384 yards and five touchdowns against the Chargers, and Houston leads the league with 29 sacks, tied for first. Cleveland has been sacked a league-high 38 times. Shedeur Sanders started last week, but Deshaun Watson, back from a concussion, is the listed depth chart starter. We favor the Texans whichever quarterback Cleveland uses. The Browns need quick throws and a better run game, which averages just 97 yards per game.

Minnesota Vikings vs Green Bay Packers prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Vikings 34%; Packers 69%.
• What to watch: Kyler Murray's hamstring and Minnesota's quarterback choice.

Carson Wentz went 8-of-25 for 81 yards with two interceptions in the loss to Buffalo, while Kyler Murray, the depth chart starter, is expected back from a hamstring injury. Minnesota's defense gives up 14.5 points per game, best in the league. Green Bay lacks Josh Jacobs, who is out, and averages 68 rushing yards per game. We give the Packers a slight edge because Jordan Love threw for 372 yards last week. The Vikings need their pass rush to make Love hold the ball.

Jacksonville Jaguars vs Tennessee Titans prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Jaguars 85%; Titans 17%.
• What to watch: Jacksonville's turnover margin against Cam Ward.

Jacksonville leads the league with a plus-nine turnover margin and scores 28.6 points per game behind Trevor Lawrence. Tennessee averages 18.0 points and 272 yards per game, and Cam Ward is the listed starter at quarterback. That mismatch in ball security points one way. We favor the Jaguars. The Titans can only change it if their defense turns its eight interceptions into extra possessions and Ward makes the most of short fields.

Miami Dolphins vs Indianapolis Colts prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Dolphins 45%; Colts 57%.
• What to watch: Malik Willis' groin and Miami's run game against the Colts front.

Malik Willis is questionable with a groin injury, and a Miami offense scoring 15.8 points per game cannot afford to lose him. Indianapolis allows 27.7 points per game and 137 rushing yards per game, both near the bottom of the league. The Colts sit tied for 31st in turnover margin, so Daniel Jones cannot give Miami extra possessions. We lean toward the Colts. Miami has to run the ball and keep Willis upright.

Carolina Panthers vs New Orleans Saints prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Panthers 49%; Saints 52%.
• What to watch: Bryce Young against New Orleans' run defense.

Bryce Young completed 28 of 39 passes for 276 yards and three touchdowns against Denver. He now faces a Saints defense allowing 134 rushing yards per game, 29th in the league. New Orleans also sits 28th in turnover margin, which makes Tyler Shough's ball security the bigger issue. We give the Panthers a narrow edge. Carolina's own defense allows 27.4 points per game, so the Saints stay in the game if the run game keeps the chains moving.

Buffalo Bills vs New York Jets prediction

• Date: Sunday, November 15.
• Kickoff: 1:00 p.m. ET.
• OG win probabilities: Bills 81%; Jets 22%.
• What to watch: Buffalo's run game against the Jets front.

Buffalo leads the league at 32.0 points per game and ranks second with 147 rushing yards per game. The Jets allow 128 rushing yards per game, 26th, and their defense has one interception all season. Josh Allen threw an interception in the win over Minnesota, but the matchup favors the Bills. We favor Buffalo. The Jets need Geno Smith to sustain drives against a Buffalo run defense that allows 92 yards per game.

Seattle Seahawks vs Las Vegas Raiders prediction

• Date: Sunday, November 15.
• Kickoff: 4:05 p.m. ET.
• OG win probabilities: Seahawks 64%; Raiders 38%.
• What to watch: Drew Lock's oblique and Seattle's pass protection.

Drew Lock is in line to start again with Sam Darnold out, and Seattle coach Mike Macdonald said Lock had a good exam on his oblique. Seattle's defense allows 89 rushing yards per game, fourth best, against a Raiders run game averaging 71, 31st in the league. Las Vegas also allows 29.8 points per game, the most in the league. Seattle gets our pick. Kirk Cousins must avoid a repeat of his three-interception game to keep Las Vegas close.

Los Angeles Rams vs Arizona Cardinals prediction

• Date: Sunday, November 15.
• Kickoff: 4:05 p.m. ET.
• OG win probabilities: Rams 81%; Cardinals 22%.
• What to watch: Arizona's quarterback situation against the Rams' offense.

Gardner Minshew II is listed as expected back, but reports describe an elbow injury that may keep him from playing. Arizona also has Michael Wilson out and averages just 19.8 points per game. Matthew Stafford and a Rams offense gaining 380 yards per game face a Cardinals defense allowing 28.3 points per game. We favor the Rams. Arizona can only stay in this game if its quarterback holds up and the offense finishes drives.

San Francisco 49ers vs Dallas Cowboys prediction

• Date: Sunday, November 15.
• Kickoff: 4:25 p.m. ET.
• OG win probabilities: 49ers 68%; Cowboys 35%.
• What to watch: San Francisco's protection for Brock Purdy.

San Francisco has allowed only eight sacks, the fewest in the league, and Brock Purdy threw two touchdowns in the win over Las Vegas. Dallas allows 147 rushing yards per game, 31st, with a pass rush of 17 sacks. Brandon Aiyuk is out for San Francisco and Jake Ferguson is out for Dallas. We lean toward the 49ers. The Cowboys need Dak Prescott, who threw for 335 yards last week, to keep scoring against a San Francisco defense allowing 81 rushing yards per game.

Pittsburgh Steelers vs Cincinnati Bengals prediction

• Date: Sunday, November 15.
• Kickoff: 8:20 p.m. ET.
• OG win probabilities: Steelers 37%; Bengals 66%.
• What to watch: Joe Burrow against Pittsburgh's pass rush.

Joe Burrow threw for 271 yards and three touchdowns against Atlanta, and Cincinnati scores 30.0 points per game, second in the league. Pittsburgh allows just 84 rushing yards per game, third best, and Cincinnati's own run game averages 86, 30th, so the game turns to the air. Aaron Rodgers is the listed starter for the Steelers. Cincinnati gets our pick. Pittsburgh needs its pass rush, with 26 sacks, to hurry Burrow before Cincinnati's passing game settles in.

Los Angeles Chargers vs Baltimore Ravens prediction

• Date: Monday, November 16.
• Kickoff: 8:15 p.m. ET.
• OG win probabilities: Chargers 33%; Ravens 70%.
• What to watch: Justin Herbert's finger and the Chargers' protection.

Justin Herbert is questionable with a finger injury, but X-rays were negative and coach Jim Harbaugh said he should be good to go. Los Angeles scores 15.1 points per game, the fewest in the league, and has been sacked 31 times. Baltimore is expected to start Jacoby Brissett at quarterback in place of Joe Fagnano, behind a run game averaging 138 yards, tied for fourth. We lean toward the Ravens if Brissett starts. The Chargers need clean protection for Herbert to stay close.

What could change before the Week 10 games?

Pending items include J.J. McCarthy's hip for the Giants, Patrick Mahomes' elbow for the Chiefs, Justin Herbert's finger for the Chargers, Malik Willis' groin for the Dolphins and the quarterback plans for the Browns, Vikings, Ravens and Cardinals. The probabilities above reflect the recorded market snapshot and may change as news develops. Any confirmed kickoff changes will be reflected in the schedule.

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